I work with innovative companies during their most critical stages – formation, scaling and exit.
Brendan Burke's practice centers on advising life sciences and emerging growth companies, with a particular emphasis on the unique needs of entrepreneurs and venture-backed businesses throughout their entire lifecycle. Brendan counsels clients from the earliest stages of entity formation and founder arrangements, through angel and venture capital financings, to strategic exits such as mergers and acquisitions. Brendan has played a key role in numerous high-profile private placements, guiding biotechnology and regenerative medicine companies through significant funding rounds, including multi-million-dollar Seed, Series A, and Series B financings. He is a trusted advisor to both innovative companies and the investors who support them, including venture capital funds, angel investors, growth equity firms, and corporate venture arms—guiding them through investments, portfolio company exits, and other strategic transactions.
Brendan's experience spans a range of industries, with a significant focus on life sciences, technology, and cannabis. He is recognized for his deep understanding of the challenges and opportunities facing companies in highly regulated and rapidly evolving sectors, and he provides tailored legal guidance at every stage of growth. Brendan is frequently sought after for his insights on structuring complex transactions and navigating the regulatory landscape, particularly in the life sciences and cannabis industries.
Brendan's leadership and commitment to client success have earned him recognition by Best Lawyers as "One to Watch." He is an active participant in industry events and regularly shares his expertise with entrepreneurial and investor communities.
Satellite Bio, a regenerative medicine company, in raising $110 million in Seed and Series A funding, led by aMoon Growth with participation from prior Seed stage investors
Alyone Therapeutics, biotechnology company pioneering next-generation precision central nervous system (CNS) therapies, in closing $23 million in funding from funds affiliated with RTW Investments, LP
Ankyra Therapeutics, a developer of biotechnology therapeutics in its $45 million Series B Preferred Stock financing
Lucy Therapeutics a biotech company developing new ways to treat neurological disorders in its Series A financing
Glympse Bio a biotechnology company advancing the way diseases are understood, tracked and treated in its $46.7 million Series B financing
Amagma which specializes in the discovery and development of antibody therapeutics against inflammatory diseases in its $16.4 million Series A deal
MERGERS & ACQUISTIONS
Columbia Care, a cultivator, manufacturer and provider of cannabis products, in its acquisition of vertically integrated cannabis company Medicine Man Denver, for upfront consideration of $42 million and a potential additional milestone payment in 2022 if certain performance targets are met
OnShape, creators of the first Software as a Service (SaaS) product development platform that unites robust computer aided design (CAD) with powerful data management and collaboration tools, in signing a definitive agreement to sell the business to global technology company PTC for approximately $470 million
Fiera Comox Partners, an independent investment manager providing innovative investment solutions to a wide range of investors through private global investment strategies in private equity and agriculture, in its acquisition of Vermont-based Sweet Tree Holdings 1, LLC (d/b/a The Maple Guild), the world’s largest producer of organic maple syrup and related products
The Boston Consulting Group, a global management consulting firm, in its acquisition of assets of world-class digital design lab MAYA Design
L2, a business intelligence firm that benchmarks the digital performance of consumer brands, in its acquisition by Gartner (NYSE: IT), an information technology research and advisory company
Mill Road Capital, a private investment firm focused on investing in publicly traded micro-cap companies in the US and Canada, in the going private acquisition of Skullcandy (Nasdaq; SKUL), a creator of world-class audio experiences through its Skullcandy and Astro Gaming brands, after a contested process
CloudLock, an industry leader in cloud security for multiple platforms, in its $300 million cash acquisition by Cisco Systems
Mill Road Capital in its acquisition of Mother’s Market & Kitchen
Honors & Involvement
HONORS
Best Lawyers: Ones to Watch - Corporate Governance and Compliance Law (2020-2025), Mergers & Acquisitions Law (2023-2025) and Venture Capital Law (2023-2025)
INVOLVEMENT
Boston Bar Association, Member
Other Events
"Life Sciences and the Law: Negotiating the Term Sheet with your Venture Investor," Financial Poise and National Law Review Webinar (July 2026)
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