Lawrence Tardibono, Ph.D.

I work with clients in the biotech and pharma industry to prepare patent applications and strategically develop patent portfolios.

Dr. Lawrence Tardibono’s practice focuses on the preparation and prosecution of U.S. and foreign patent applications in the areas of pharmaceuticals, chemicals, and materials science. His technical expertise is in the area of organic and medicinal chemistry and was developed during a combined ten years of work in the pharmaceutical industry and academia.

Lawrence’s graduate and post-doctoral research focused on methodology development and synthesis of biologically relevant molecules. He earned a Ph.D. in Organic Chemistry from the University of Notre Dame in the laboratory of Professor Marvin J. Miller and was then a post-doctoral research associate in the laboratory of Professor Tehshik Yoon at the University of Wisconsin – Madison. He also worked as a medicinal chemist at a pharmaceutical company preparing potential anti-cancer drug molecules.

Related Industries

Life Sciences

Related Practices

Education

Fordham University School of Law, J.D., 2018
University of Notre Dame, Ph.D., Organic Chemistry, 2010
College of the Holy Cross, B.A., Chemistry, 2002

Bar and Court Admissions

BAR ADMISSIONS

New York
U.S. Patent & Trademark Office (Agency)

Experience

Managed patent portfolios for a broad range of clients including leading research universities, emerging biotechnology startups, and pharmaceutical companies.
Prepared and prosecuted patent applications related to bioactive small molecules, complex natural product derivatives, crystalline forms, synthetic methods, methods of treating disease, and nutraceuticals.
Developed and managed patent portfolio for early-stage pharmaceutical company that was recently acquired by a large pharmaceutical company. A drug composition in that portfolio is now in Phase 2 clinical trials.
Prepared numerous patent applications for a major research university which developed into a portfolio that was licensed to a biopharmaceutical company. A drug composition in that portfolio is now in Phase 3 clinical trials.
Prepared patent applications and obtained several patents for an independent inventor who then launched a start-up company in the nutraceutical field.

Publications

Tardibono, L.; Miller, M. J.; Balzarini, J. Enantioselective Syntheses of Carbocyclic Nucleosides 5'-Homocarbovir, epi-4'-Homocarbovir and their Cyclopropylamine Analogs Using Facially Selective Pd-Mediated Allylations. Tetrahedron 2011, 67, 825-829.
Tardibono, L.; Patzner, J.; Cesario, C.; Miller, M. J. Palladium-Catalyzed Decarboxylative Rearrangements of Allyl 2,2,2-Malonates: Direct Access to Homoallylic Esters. Org. Lett. 2009, 11, 4076-4079.
Tardibono, L.; Miller, M. J. Synthesis and Anti-Cancer Activity of New Hydroxamic Acid Containing 1,4-Benzodiazepines. Org. Lett. 2009, 11, 1575-1578.
Cesario, C.; Tardibono, L.; Miller, M. J. Syntheses of Carbocyclic Aminonucleosides and (–)-epi-4'-Carbocyclic Puromycin: Application of Pd(0)/Indium Iodide Allylations and Tethered Aminohydroxylations. Tetrahedron Lett. 2010, 51, 3053-3056.
Cesario, C.; Tardibono, L.; Miller, M. J. Titanocene (III) Chloride-Mediated Reductions of Oxazines, Hydroxamic Acids, and N-Hydroxy Carbamates. J. Org. Chem. 2009, 74, 448-451.
Castelhano, A.; Crew, A.; Dong, H.; Li, A.; Qiu, L.; Smith, A.; Tardibono, L.; Zhang, T. (Arylamidoaryl)squaramide compounds. U.S. Patent No. 7,829,717, filed September 15, 2005, and issued November 9, 2010.
Bloxham, J.; Crew, A.; Honda, A.; Li, A.; Panicker, B.; Wynne, M. G.; Tardibono, L. (2-carboxamido)(3-Amino) thiophene compounds. U.S. Patent No. 7,696,225, filed October 26, 2004, and issued April 13, 2010.