Watkins

Lucas Watkins, Ph.D.

Partner
Registered Patent Attorney; Co-Chair, Patent Prosecution Practice
New York

I help clients protect their innovations by developing comprehensive patent portfolio and enforcement strategies.

Lucas Watkins advises clients in the chemical, pharmaceutical, biotechnology, and greentech industries on their intellectual property needs, including patent portfolio development and litigation strategies.

In his counseling work, Lucas advises clients on portfolio strategy, provides opinions, and prepares and prosecutes patent applications. As part of that work, he manages global patent portfolios for a variety of companies ranging from early-stage startups to publicly traded companies, in technology areas including pharmaceuticals, medical devices, chemical manufacturing processes, and catalysts. He has also litigated patent infringement and trade secret actions before U.S. district courts, international arbitration panels, the U.S. International Trade Commission, and the Patent Trial and Appeal Board.

Lucas has a background in chemistry, biochemistry, and molecular biology. For his Ph.D. research, he used single-molecule FRET to study conformational dynamics in proteins. Lucas also designed and built a single-molecule microscope and developed novel statistical methods to efficiently analyze photon arrival time data. His prior research examined photoisomerization mechanisms in constrained stilbene analogues.

Education

  • Harvard Law School, J.D.
  • University of California, Berkeley, Ph.D., Physical Chemistry
  • Florida State University, B.S., Chemistry and Biochemistry

Bar and Court Admissions

BAR ADMISSIONS
  • New York
  • U.S. Patent & Trademark Office (Agency)
COURT ADMISSIONS
  • U.S. District Court for the Southern District of New York
  • U.S. District Court for the Eastern District of New York
  • U.S. Court of Appeals for the Federal Circuit

Experience

PATENT PROSECUTION
  • Patent prosecution counsel for portfolios protecting various marketed pharmaceuticals
  • Patent prosecution counsel for various early-stage companies developing pharmaceuticals
  • Patent prosecution counsel for company manufacturing sustainable products, including aviation fuel, from carbon dioxide 
  • Patent prosecution counsel for various major research universities
LICENSING & STRATEGIC ALLIANCES
  • LigaChem Biosciences (KRX: 141080), a clinical stage biopharmaceutical company, in two transactions involving the license of LigaChem technology to Ono Pharmaceutical (TSE/TYO: 4528), to grow Ono’s oncology portfolio:
    • an exclusive license to LCB97, a pre-clinical stage antibody-drug conjugate (ADC) aimed at being a first-in-class drug in the field of solid tumors, for upfront and milestone payments of up to $700 million, plus tiered royalties; and
    • a research collaboration and license agreement to generate novel ADC candidates leveraging LigaChem’s ConjuAll™ ADC platform, granting Ono an exclusive global right to ADC candidates to be generated against multiple targets selected by Ono, for a target exclusivity fee, milestone payments, and tiered royalties.
LITIGATION & ARBITRATION
  • Counsel for patent owner in patent infringement litigation concerning polymer dyes and related IPRs
  • Counsel for complainant in a section 337 (ITC) action concerning herbicide manufacturing processes.
  • Counsel for respondent in an ICC arbitration concerning joint development of a pharmaceutical.
  • Counsel for patent owner in a patent infringement lawsuit and related IPR concerning PCR diagnostic techniques.

Other Publications

  • Etan Chatlynne, Stephen Kenny & Lucas Watkins, Investigating Patent Law’s Presumption of Validity Part II: An Empirical Analysis of How Unconsidered Evidence And Evidentiary Standards Affect Jury Verdicts, 2011 Cardozo L. Rev. De Novo 46
  • Lucas Watkins, How States can Protect their Policies in Federal Class Actions, 32 Campbell L. Rev. 285 (2010)
  • Lucas Watkins, Ph.D. Dissertation, Optimal Statistical Methods for Analysis of Single-Molecule Data
  • J.A. Hanson, K. Duderstadt, Lucas Watkins, S. Bhattacharyya, J. Brokaw, J.-W. Chu, and H. Yang, Illuminating the Mechanistic Roles of Enzyme Conformational Dynamics, 104 Proc. Natl. Acad. Sci. U.S.A., 18055 (2007)
  • Lucas Watkins, H. Chang, and H. Yang, Quantitative Single-Molecule Conformational Distributions: A Case Study with Poly-(L-proline), 110 J. Phys. Chem. A 5191 (2006)
  • Lucas Watkins and H. Yang, Detection of Intensity Change Points in Time-Resolved Single Molecule Measurements, 109 J. Phys. Chem. B 617 (2005)
  • Lucas Watkins and Haw Yang, Information Bounds and Optimal Analysis of Dynamic Single Molecule Measurements, 86 Biophysical Journal 4015 (2004)

Speaking Engagements

  • “Patenting Strategies for Small Molecule Drugs," Drug Hunter Podcast (November 2025)
  • "The Next Chapter in Climate Investing: A GP-Led Conversation on Strategy, Policy, and Liquidity," Impact Capital Managers (September 2025)
  • "Hatch-Waxman / Orange Book," Foley Hoag FDA and Life Sciences Summit (May 2024)
  • "Intellectual Property and Trademark Considerations and Timing," Foley Hoag FDA and Life Sciences Summit (May 2024)
  • "Foley Hoag Life Sciences Jumpstart Series: From Startup to Scale-Up," Foley Hoag Webinar (October 2023)